Archive for the Category »Coffee & Caffeine «

Coffee is an essential start of the day for many of us. Research has proven that coffee is not all that bad for you. Coffee has proven to help maintain a good immune system, protect the liver against cancer, and one of the most interesting about coffee is that it helps maintain the memory.

A couple of cups of coffee a day may be all that is needed to reverse the effects of Alzheimer’s disease, new research suggests.

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US neuroscience Gary Arendash said: “The new findings provide evidence that caffeine could be a viable ‘treatment’ for established Alzheimer’s disease, and not simply a protective strategy. That’s important because caffeine is a safe drug for most people. It easily enters the brain, and it appears to directly affect the disease process.” As the leading researcher, he plans to follow up the initial results from animal experiments with human patient trials.

A key aspect of Alzheimer’s is sticky clumps of abnormal protein in the brain called beta amyloid plaques. Mice with a rodent equivalent of the disease showed a 50 per cent reduction in levels of amyloid protein in their brains after scientists spiked their drinking water with caffeine. The change was reflected in their behaviour as the mice developed better memories and quicker thinking.

Dr Arendash’s team, from the Florida Alzheimer’s Disease Research Centre in Tampa, studied 55 mice, genetically engineered to develop dementia symptoms identical to those of Alzheimer’s. At the age of 18 to 19 months, about 70 in human years, the mice were showing signs of memory impairment. The researchers then gave half the mice water containing caffeine while the other half continued to drink ordinary water.

Humans receiving an equivalent dose for their body weight would be consuming two cups of strong “coffee shop” coffee a day.

At the end of the two-month study, the caffeine-drinking mice performed far better on tests of memory and thinking than mice given “straight” water. Their memories were as sharp as those of healthy older mice without dementia. Almost half the abnormal protein previously seen when the brains of Alzheimer’s mice were examined had vanished after two months. The study was published online in the Journal of Alzheimer’s Disease.

However, the scientists found no evidence that caffeine boosted the mental performance of healthy young brains. Normal mice given caffeinated drinking water throughout their lives had memories no better than those raised on regular water when they reached old age.

The Power Of Caffeine

THE PREVAILING THEORY of why caffeine increases alertness took shape only in the early 1970s. The theory holds that caffeine interferes with the depressant effects of adenosine, which is one of the chemicals that the body makes to control neural activity~ Adenosine triggers a serieThe Power Of Caffeine

THE PREVAILING THEORY of why caffeine increases alertness took shape only in the early 1970s. The theory holds that caffeine interferes with the depressant effects of adenosine, which is one of the chemicals that the body makes to control neural activity~ Adenosine triggers a series of slowing effects: it depresses mood and alertness, lowers the need to urinate and slows gastric secretion and respiration. After it is released by nerve endings in the brain, adenosine must reach receptors on the surface of certain brain cells in order to work. Caffeine, the theory has it, acts as an adenosine impostor. Molecules of caffeine counterfeit molecules of adenosine, locking into the adenosine receptors on brain cells. They fool the body into thinking that adenosine is circulating, but they produce no depressive effect of their own.

Caffeine speeds you up, then, by not slowing you down. Its effects are the opposite of what adenosine does: it makes you feel brighter and more alert, increases gastric secretion, makes you urinate more and stimulates respiration.

Proponents of caffeine speak of its ability to increase vigilance and heighten the ability to perform various tasks. Its effects are most pronounced, how- ever, when compared with performance levels that are low because of fatigue, boredom or caffeine abstinence. Too, its effects seem to vary by personality type. For example, caffeine appears to help extroverts keep performing vigilance tasks better than introverts, who can evidently plow through such tasks unassisted.

Despite the generations of writers who have thought that coffee helped them think more clearly, caffeine seems only to increase intellectual speed, not intellectual power. Subjects in experiments do things like read and fill out crossword puzzles faster-but not, unfortunately, more accurately.

Caffeine quickens reaction time and can enhance both hand-eye coordination and the capacity of muscles to work. This boost to overall endurance has led to its use by cyclists and runners. But caffeine also has a diuretic effect, increasing frequency of urination. Caffeinated drinks are thus dehydrating, good for neither athletes nor flyers: dehydration is one of the worst problems of air travel and a prime cause of jet-lag.

Caffeine speeds up the metabolism and makes you burn calories faster, although not so much faster that it will help you lose weight. Its inclusion in over-the-counter diet pills in place of prescription-only amphetamines (“speed”) seems to be largely ineffective. Amphetamines, which diminish appetite, work differently than caffeine does on the brain.

This general quickening does not mean that coffee can sober you up – either black or with milk. Your motor functions will be just as impaired by alcohol as they were minutes before you downed that cup of coffee, and even if you feel more awake, you’re just as dangerous a driver. Similarly, caffeine does not counteract the effects of phenobarbital and other barbiturates. It does, however, help reverse the impairment of cognitive activity caused by benzodiazepines, the compounds that are the basis of Valium and many other tranquilizers. This reversal affects how you think as opposed to how fast you react. If you are taking a muscle relaxant or tranquilizer that you think might be one of these compounds, ask your doctor; he or she will probably advise you not to defeat the effects of the drug by drinking coffee.

Some researchers speculate that a similar restorative effect on cognitive activity might take place in the interaction between caffeine and alcohol, but no one yet knows. Remember, though, that the question is whether caffeine can help you think more clearly after you have drunk alcohol – not whether it will improve your reflexes. No one imagines that coffee can make you a safer driver after you’ve been drinking.

Besides being a self-prescribed antidepressant and alertness drug, caffeine has been shown to be useful to people with asthma, since it works as a bronchodilator, meaning that it widens the air passages in the lungs and eases breathing. It might even be something of an aphrodisiac, if the results of a University of Michigan study can be generally applied: the study showed that older subjects were more likely to be sexually active if they were coffee drinkers than if they were not.


More Buzz Than You Bargained For! 

Associated Press

Does that cup of decaffeinated coffee give you a jolt? It may, because almost all decaf coffee contains some caffeine, a new University of Florida study shows.

The results could have implications for people told to avoid caffeine because of certain medical conditions such as high blood pressure, kidney disease or anxiety disorders, according to the study reported in this month’s Journal of Analytical Toxicology.

“If someone drinks five to 10 cups of decaffeinated coffee a day, the dose of caffeine could easily reach the level in a cup or two of caffeinated coffee,” said co-author Dr. Bruce Goldberger, a professor and director of the university’s William R. Maples Center for Forensic Medicine.

Researchers purchased 10 cups of 16-ounce drip-brewed coffee from nine national chains and local coffee houses and tested them for caffeine content.

Instant decaffeinated Folgers Coffee Crystals didn’t have any caffeine, but the others contained caffeine ranging from 8.6 milligrams to 13.9 milligrams. Typically, 16 ounces of drip-brewed coffee contain about 170 milligrams of caffeine.

Researchers also analyzed 12 samples of Starbucks decaffeinated espresso and brewed decaffeinated coffee. The espresso drinks had from 3 milligrams to 15.8 milligrams each, while the brewed coffee had from 12 to 13.4 milligrams per 16-ounce drink.

Even moderate caffeine levels can increase heart rate, blood pressure, agitation and anxiety in some people, Goldberger said.

Dr. Roland Griffiths, a professor of behavioral biology and neuroscience at Johns Hopkins School of Medicine, said caffeine as low as 10 milligrams can cause behavioral effects in sensitive individuals. Some popular espresso drinks, such as lattes, can deliver as much caffeine as a can of Coca-Cola, about 31 milligrams.

“The important point is that decaffeinated coffee is not the same as caffeine-free,” Griffiths said.

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